Gene symbol | CD276 | Synonyms | 4Ig-B7-H3, B7-H3, B7H3, B7RP-2 | Type of gene | protein-coding |
Chromosome | 15 | Map location | 15q24.1 | dbXrefs | |
Description | CD276 molecule |
Gene symbol | ERBB2 | Synonyms | CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19, NEU, NGL, TKR1, VSCN2, c-ERB-2, c-ERB2, p185(erbB2) | Type of gene | protein-coding |
Chromosome | 17 | Map location | 17q12 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | erb-b2 receptor tyrosine kinase 2 |
Gene symbol | FOLH1 | Synonyms | FGCP, FOLH, GCP2, GCPII, NAALAD1, PSM, PSMA, mGCP | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11p11.12 | dbXrefs | |
Description | folate hydrolase 1 |
GTO ID | GTC2383 |
Trial ID | NCT04433221 |
Disease | Sarcoma | Ewing Sarcoma | Osteosarcoma |
Altered gene | GD2|PSMA|HER2|CD276 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | GD2/PSMA/HER2/B7-H3 CAR-T cells |
Co-treatment | sarcoma vaccines |
Phase | Phase1|Phase2 |
Recruitment status | Recruiting |
Title | Combination Immunotherapy Targeting Sarcomas |
Year | 2020 |
Country | China |
Company sponsor | Shenzhen Geno-Immune Medical Institute |
Other ID(s) | GIMI-IRB-20007 |
Cohort 1 | |||||||||||
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