Basic Information

Gene symbol CD276 Synonyms 4Ig-B7-H3, B7-H3, B7H3, B7RP-2 Type of gene protein-coding
Description CD276 molecule


Gene symbol ERBB2 Synonyms CD340, HER-2, HER-2/neu, HER2, MLN 19, MLN-19, NEU, NGL, TKR1, VSCN2, c-ERB-2, c-ERB2, p185(erbB2) Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description erb-b2 receptor tyrosine kinase 2

Gene symbol FOLH1 Synonyms FGCP, FOLH, GCP2, GCPII, NAALAD1, PSM, PSMA, mGCP Type of gene protein-coding
Description folate hydrolase 1

GTO ID GTC2383
Trial ID NCT04433221
Disease Sarcoma | Ewing Sarcoma | Osteosarcoma
Altered gene GD2|PSMA|HER2|CD276
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment GD2/PSMA/HER2/B7-H3 CAR-T cells
Co-treatment sarcoma vaccines
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleCombination Immunotherapy Targeting Sarcomas
Year2020
CountryChina
Company sponsorShenzhen Geno-Immune Medical Institute
Other ID(s)GIMI-IRB-20007

Clinical Result

Cohort 1
Administration route None
Dosage 1E6~1E7 cells/kg
Donor type Autologous
Pts 20
Age Child, Adult, Older_Adult

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