Basic Information

Gene symbol DSG3 Synonyms ABOLM, CDHF6, PVA Type of gene protein-coding
Description desmoglein 3

GTO ID GTC2375
Trial ID NCT04422912
Disease Pemphigus Vulgaris
Altered gene DSG3
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment DSG3-CAART|CABA-201
PhasePhase1
Recruitment statusRecruiting
TitleOpen-label Study to Determine the Maximum Tolerated Dose of DSG3-CAART in Mucosal-dominant PV Patients (mPV)
Year2020
CountryUnited States
Company sponsorCabaletta Bio
Other ID(s)CAB-101

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Autologous
Pts 39
Age Adult, Older_Adult

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