Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC2373
Trial ID NCT04419909
Disease B-Cell Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment Kymriah|Tisagenlecleucel
Generation2nd
PhasePhase1
Recruitment statusNot Recruiting
TitleRetreatment With CTL019/CTL119
Year2020
CountryUnited States
Company sponsorUniversity of Pennsylvania
Other ID(s)UPCC 40419|834286
Vector information
Vectorlentivirus
ConstructscFv-4-1BB-CD3ζ

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Autologous
Pts 12
Age Adult, Older_Adult
Lymph depletion Yes

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