Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC2358
Trial ID NCT04404660
Disease B-Cell Acute Lymphoblastic Leukemia
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment AUTO1|Obecabtagene autoleucel|obe-cel
PhasePhase1|Phase2
Recruitment statusActive, Not Recruiting
TitleA Study of CD19 Targeted CAR T Cell Therapy in Adult Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukaemia (ALL)
Year2020
CountryUnited States
Company sponsorAutolus Limited
Other ID(s)FELIX (AUTO1-AL1)|2019-001937-16

Clinical Result

Cohort 1
Administration route None
Dosage 41E7 cells
Donor type Autologous
Pts 153
Age Adult, Older_Adult
Lymph depletion Yes

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