Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

GTO ID GTC2356
Trial ID NCT04394650
Disease Multiple Myeloma
Altered gene BCMA
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CC-98633
PhasePhase1
Recruitment statusActive, Not Recruiting
TitleA Study of CC-98633, BCMA-targeted Chimeric Antigen Receptor (CAR) T Cells, in Participants With Relapsed and/or Refractory Multiple Myeloma
Year2020
CountryTexas
Company sponsorJuno Therapeutics, a Subsidiary of Celgene
Other ID(s)CC-98633-MM-001|U1111-1251-3435

Clinical Result

Cohort 1
Administration route intravenous infusion
Pts 54
Age Adult, Older_Adult
Lymph depletion Yes
Outcome 16/54(CR); 32/54(PR); 98.1%(ORR)
Adverse reactions 80.0%(CRS)
References DOI: 10.1182/blood-2022-160038

Relationship Graph

Overview of Knowledge Graph