Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC2354
Trial ID NCT04384393
Disease B-Cell Malignancy
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment ThisCAR-T19
PhasePhase1
Recruitment statusRecruiting
TitleSafety and Efficacy of ThisCART19 in Patients With Refractory or Relapsed B Cell Malignancies
Year2020
CountryChina
Company sponsorFundamenta Therapeutics, Ltd.
Other ID(s)ThisCART19

Clinical Result

Cohort 1
Administration route None
Dosage 0.2~60E6 cells/kg
Donor type Allogeneic
Pts 8
Age Child, Adult, Older_Adult
Outcome 5/8(CR); 1/8(PR)
Adverse reactions no ≥3 grade of CRS or ICANS and no evidence of GvHD reaction
References DOI: 10.1097/01.HS9.0000843948.58401.85

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