Basic Information

Gene symbol GPC3 Synonyms DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1 Type of gene protein-coding
Description glypican 3

GTO ID GTC2350
Trial ID NCT04377932
Disease Wilms' Tumor | Liver Cancer | Rhabdomyosarcoma | Yolk Sac Tumor | Liposarcoma
Altered gene GPC3
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment AGAR T cells
PhasePhase1
Recruitment statusRecruiting
TitleInterleukin-15 Armored Glypican 3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors
Year2020
CountryUnited States
Company sponsorBaylor College of Medicine
Other ID(s)H-47757 AGAR

Clinical Result

Cohort 1
Administration route None
Dosage 3E7 cells/m^2, 1E8 cells/m^2, 3E8 cells/m^2, 1E9 cells/m^2
Pts 24
Age Child, Adult

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