Basic Information

Gene symbol CD38 Synonyms ADPRC 1, ADPRC1, cADPR1 Type of gene protein-coding
Gene perturbation-related omics dataset PertOrg
Description CD38 molecule

GTO ID GTC2346
Trial ID NCT04351022
Disease Acute Myeloid Leukemia
Altered gene CD38
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD38 CAR-T cells
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleCD38-targeted Chimeric Antigen Receptor T Cell (CART) in Relapesd or Refractory Acute Myeloid Leukemia
Year2020
CountryChina
Company sponsorThe First Affiliated Hospital of Soochow University
Other ID(s)UnicarTherapy2020001

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 5~20E6 cells/kg
Pts 2
Age Child, Adult, Older_Adult
Outcome 2/2(CR)
Adverse reactions 2/2(fever)
References PMID: 36524116

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