Basic Information

Gene symbol ACE2 Synonyms ACEH Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description angiotensin converting enzyme 2

Gene symbol KLRK1 Synonyms CD314, D12S2489E, KLR, NKG2-D, NKG2D Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description killer cell lectin like receptor K1

GTO ID GTC2340
Trial ID NCT04324996
Disease COVID-19
Altered gene NKG2D|ACE2
Therapeutic/Target gene Target gene
TherapyCAR-NK cell
Treatment NKG2D/ACE2 CAR-NK cells
PhasePhase1|Phase2
Recruitment statusUnknown
TitleA Phase I/II Study of Universal Off-the-shelf NKG2D-ACE2 CAR-NK Cells for Therapy of COVID-19
Year2020
CountryChina
Company sponsorChongqing Public Health Medical Center
Other ID(s)ChongqingPublicHMC

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1E8 cells/kg
Pts 90
Age Adult, Older_Adult
Lymph depletion Yes

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