Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC2329
Trial ID NCT04303247
Disease B-Cell Lymphoma
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD22 CAR-T cells
PhaseEarly_Phase1
Recruitment statusUnknown
TitleCD19 and CD22 Dual-targeted CAR-T Cells for Relapsed or Refractory B-NHL
Year2020
CountryChina
Company sponsorXinqiao Hospital of Chongqing
Other ID(s)dual CD19/CD22 CAR-T

Clinical Result

Cohort 1
Administration route None
Dosage 3E5 cells/kg, 6E5 cells/kg, 1E6 cells/kg
Pts 30
Age Adult, Older_Adult
Lymph depletion Yes

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