Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

GTO ID GTC2326
Trial ID NCT04295018
Disease Multiple Myeloma
Altered gene BCMA
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment C-CAR088
PhasePhase1
Recruitment statusUnknown
TitleA Study of BCMA-directed CAR-T Cells Treatment in Subjects With r/r Multiple Myeloma
Year2019
CountryChina
Company sponsorPeking Union Medical College Hospital
Other ID(s)0203-007
Vector information
Vectorlentivirus
Transgene/Inserted genescFv of C-CAR088 is derived from a human IgG1 antibody; 4-1BB; CD3ζ

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1~9E6 cells/kg
Donor type Autologous
Pts 10
Age Adult, Older_Adult
References PMID: 36100310

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