Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC2324
Trial ID NCT04289220
Disease B-Cell Acute Lymphoblastic Leukemia | B-Cell Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19 CAR-T cells
Generation3rd
PhasePhase1
Recruitment statusRecruiting
TitleAnti-CD19 CAR in PiggyBac Transposon-Engineered T Cells for Relapsed/Refractory B-cell Lymphoma or B-cell Acute Lymphoblastic Leukemia
Year2020
CountryChina
Company sponsorYan'an Affiliated Hospital of Kunming Medical University
Other ID(s)2019-1-N-25318000002027
Vector information
VectorpiggyBac transposon system
ConstructscFv-CD28-4-1BB-CD3ζ

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1~2.5E6 cells/kg, one infusion
Pts 10
Age Adult, Older_Adult

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