Gene symbol | KLRK1 | Synonyms | CD314, D12S2489E, KLR, NKG2-D, NKG2D | Type of gene | protein-coding |
Chromosome | 12 | Map location | 12p13.2 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | killer cell lectin like receptor K1 |
GTO ID | GTC2307 |
Trial ID | NCT04270461 |
Disease | Colon Cancer | Hepatocellular Carcinoma | Glioblastoma | Medulloblastoma |
Altered gene | NKG2D |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | KD-025 CAR-T cells |
Generation | 2nd |
Phase | Phase1 |
Recruitment status | Withdrawn |
Title | NKG2D-based CAR T-cells Immunotherapy for Patient With r/r NKG2DL+ Solid Tumors |
Year | 2020 |
Country | China |
Company sponsor | Jiujiang University Affiliated Hospital |
Other ID(s) | JiujiangUH |
Cohort 1 | |||||||||||
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