Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC2290
Trial ID NCT04234061
Disease Mantle Cell Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment Kymriah|Tisagenlecleucel
Co-treatment Ibrutinib
Generation2nd
PhasePhase2
Recruitment statusActive, Not Recruiting
TitleClinical Trial to Assess The Efficacy and Safety of the Combination of Tisagenlecleucel And Ibrutinib in Mantle Cell Lymphoma
Year2020
CountryAustralia
Company sponsorPeter MacCallum Cancer Centre, Australia
Other ID(s)19/008
Vector information
Vectorlentivirus
ConstructscFv-4-1BB-CD3ζ

Clinical Result

Cohort 1
Administration route intravenous drip
Donor type Autologous
Pts 20
Age Adult, Older_Adult
Lymph depletion Yes

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