Gene symbol | GH1 | Synonyms | GH, GH-N, GHB5, GHN, IGHD1A, IGHD1B, IGHD2, hGH-N | Type of gene | protein-coding | |
Chromosome | 17 | Map location | 17q23.3 | dbXrefs | Entrez:2688 MIM:139250 HGNC:HGNC:4261 Ensembl:ENSG00000259384 AllianceGenome:HGNC:4261 | |
Description | growth hormone 1 |
Gene symbol | LIPF | Synonyms | GL, HGL, HLAL | Type of gene | protein-coding | |
Chromosome | 10 | Map location | 10q23.31 | dbXrefs | Entrez:8513 MIM:601980 HGNC:HGNC:6622 Ensembl:ENSG00000182333 AllianceGenome:HGNC:6622 | |
Description | lipase F, gastric type |
Gene symbol | UL128 | Synonyms | None | Type of gene | protein-coding | |
Chromosome | - | Map location | NC_006273.2 | dbXrefs | Entrez:3077505 - | |
Description | contains signal peptide; similar to CC chemokines; complexed with envelope glycoproteins H and L; essential in non-fibroblast cells; involved in cell entry |
Gene symbol | UL130 | Synonyms | None | Type of gene | protein-coding | |
Chromosome | - | Map location | NC_006273.2 (176984..177628, complement) | dbXrefs | Entrez:3077481 - | |
Description | envelope glycoprotein UL130 |
Gene symbol | UL131A | Synonyms | None | Type of gene | protein-coding | |
Chromosome | - | Map location | NC_006273.2 (177649..178146, complement) | dbXrefs | Entrez:3077493 - | |
Description | envelope protein UL131A |
GTO ID | GTC2289 |
Trial ID | NCT04232280 |
Disease | Human Cytomegalovirus Infection |
Altered gene | gB|gH|gL|UL128|UL130|UL131A |
Therapeutic/Target gene | Therapeutic gene |
Therapy | mRNA vaccine |
Treatment | mRNA-1647 |
Phase | Phase2 |
Recruitment status | Completed |
Title | A Phase 2, Randomized, Observer-Blind, Placebo-Controlled, Dose-Finding Trial to Evaluate the Safety and Immunogenicity of Cytomegalovirus Vaccine mRNA-1647 in Healthy Adults |
Year | 2020 |
Country | United States |
Company sponsor | ModernaTX, Inc. |
Other ID(s) | mRNA-1647-P202 |
Vector information | |||
|
Cohort1: mRNA-1647 | |||||||
|
|||||||
Cohort2: Placebo | |||||||
|