Basic Information

Gene symbol IL3RA Synonyms CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra Type of gene protein-coding
Description interleukin 3 receptor subunit alpha

GTO ID GTC2287
Trial ID NCT04230265
Disease Acute Myeloid Leukemia | Blastic Plasmacytoid Dendritic Cell Neoplasm
Altered gene CD123
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment UniCAR02-T-CD123
PhasePhase1
Recruitment statusRecruiting
TitleDose-escalating Trial With UniCAR02-T Cells and CD123 Target Module (TM123) in Patients With Hematologic and Lymphatic Malignancies
Year2020
CountryGermany
Company sponsorAvenCell Europe GmbH
Other ID(s)UC02-123-01|2019-001339-30

Clinical Result

Cohort 1
Administration route intravenous infusion
Pts 90
Age Adult, Older_Adult
Lymph depletion Yes

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