Basic Information

Gene symbol COLEC10 Synonyms 3MC3, CL-10, CL-34, CLL1 Type of gene protein-coding
Description collectin subfamily member 10

GTO ID GTC2282
Trial ID NCT04219163
Disease Acute Myeloid Leukemia
Altered gene CLL1
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CLL1 CAR-T cells
Generation2nd
PhasePhase1
Recruitment statusRecruiting
TitleChimeric Antigen Receptor T-cells for The Treatment of AML Expressing CLL-1 Antigen
Year2020
CountryUnited States
Company sponsorBaylor College of Medicine
Other ID(s)H-43516-CARMEN
Vector information
Vectorretrovirus
ConstructscFv-CD28-CD3ζ

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1E7 cells/m^2, 3E7 cells/m^2, 1E8 cells/m^2
Donor type Autologous
Pts 18
Age Child, Adult, Older_Adult
Lymph depletion Yes

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