Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol MS4A1 Synonyms B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 Type of gene protein-coding
Description membrane spanning 4-domains A1

GTO ID GTC2281
Trial ID NCT04215016
Disease Diffuse Large B-Cell Lymphoma
Altered gene CD19|CD20
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD20 CAR-T cells
PhasePhase1
Recruitment statusRecruiting
TitleSafety of Autologous Humanized Anti-CD19 and Anti-CD20 Dual Specific CAR-T Cells in Adult Patients With Diffuse Large B-cell Lymphoma
Year2019
CountryChina
Company sponsorFujian Medical University
Other ID(s)CART-19-05

Clinical Result

Cohort 1
Administration route None
Dosage 1E6 cells/kg, 3E6 cells/kg, 8E6 cells/kg
Donor type Autologous
Pts 18
Age Adult, Older_Adult
Lymph depletion Yes

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