Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD34 Synonyms None Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description CD34 molecule

GTO ID GTC2280
Trial ID NCT04214886
Disease B-Cell Lymphoma | B-Cell Acute Lymphoblastic Leukemia
Altered gene CD19|CD34
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD34 CAR-T cells
PhasePhase1
Recruitment statusActive, Not Recruiting
TitleCD19 Chimeric Antigen Receptor (CAR) T Cells for Adults With Recurrent or Refractory B Cell Malignancies
Year2019
CountryUnited States
Company sponsorLoyola University
Other ID(s)212594
Vector information
Vectorretrovirus

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 5E5 cells/kg, 1E6 cells/kg, 1.5E6 cells/kg, 2E6 cells/kg
Donor type Autologous
Pts 24
Age Adult, Older_Adult
Lymph depletion Yes

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