Gene symbol | GRB2 | Synonyms | ASH, EGFRBP-GRB2, Grb3-3, MST084, MSTP084, NCKAP2 | Type of gene | protein-coding |
Chromosome | 17 | Map location | 17q25.1 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | growth factor receptor bound protein 2 |
GTO ID | GTC2270 |
Trial ID | NCT04196257 |
Disease | Endometrial Cancer | Epithelial Ovarian Cancer | Fallopian Tube Neoplasm | Peritoneal Carcinoma |
Altered gene | GRB2 |
Therapeutic/Target gene | Target gene |
Therapy | ASO |
Treatment | BP1001|Liposomal Grb2 Antisense Oligonucleotide|Liposomal Grb-2|L-Grb-2 |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | A Phase I/Ib Study of BP1001-A (a Liposomal Grb2 Antisense Oligonucleotide) in Patients With Advanced or Recurrent Solid Tumors |
Year | 2022 |
Country | United States |
Company sponsor | Bio-Path Holdings, Inc. |
Other ID(s) | BP1001-A-101-GynOnc |
Vector information | |||
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Cohort1: BP1001-A | |||||||
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Cohort2: BP1001-A_paclitaxel | |||||||
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