| Gene symbol | CD276 | Synonyms | 4Ig-B7-H3, B7-H3, B7H3, B7RP-2 | Type of gene | protein-coding |
| Chromosome | 15 | Map location | 15q24.1 | dbXrefs | |
| Description | CD276 molecule | ||||
| GTO ID | GTC2262 |
| Trial ID | NCT04185038 |
| Disease | Germ Cell Tumor | Pineoblastoma | Brain Glioma | Brain Ependymoma | Atypical Teratoid Rhabdoid Tumor | Primitive Neuroectodermal Tumor | Choroid Plexus Carcinoma | Diffuse Midline Glioma | Childhood Medulloblastoma |
| Altered gene | CD276 |
| Therapeutic/Target gene | Target gene |
| Therapy | CAR-T cell |
| Treatment | SCRI-CARB7H3(s) |
| Generation | 2nd |
| Phase | Phase1 |
| Recruitment status | Recruiting |
| Title | Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors |
| Year | 2019 |
| Country | United States |
| Company sponsor | Seattle Children's Hospital |
| Other ID(s) | BrainChild-03 |
| Vector information | |||
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| Cohort 1 | |||||||||
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