Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC2256
Trial ID NCT04173988
Disease Childhood B-Cell Acute Lymphoblastic Leukemia
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment AlloCAR-T-19
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleStudy of alloCART-19 Cell Therapy in Pediatric Patients With Relapsed/Refractory B-Cell Acute Lymphoblastic Leukemia
Year2020
CountryChina
Company sponsorChildren's Hospital of Fudan University
Other ID(s)2019-272

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage ≤ 50kg, 0.5~5E6 cells/kg, >50kg, 0.25~2.5E8 cells
Donor type Allogeneic
Pts 6
Age Child, Adult
Lymph depletion Yes

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