Basic Information

Gene symbol KLRK1 Synonyms CD314, D12S2489E, KLR, NKG2-D, NKG2D Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description killer cell lectin like receptor K1

GTO ID GTC2252
Trial ID NCT04167696
Disease Acute Myeloid Leukemia | Myelodysplastic Syndrome
Altered gene NKG2D
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CYAD-02
PhasePhase1
Recruitment statusRecruiting
TitleStudy in Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome Patients to Determine the Recommended Dose of CYAD-02
Year2019
CountryBelgium
Company sponsorCelyad Oncology SA
Other ID(s)CYAD-02-001

Clinical Result

Cohort 1
Administration route None
Dosage 1E8 cells, 3E8 cells, 1E9 cells
Pts 27
Age Adult, Older_Adult
Lymph depletion Yes

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