Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC2247
Trial ID NCT04162353
Disease Multiple Myeloma | Lymphoplasmacytic Lymphoma
Altered gene BCMA|CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment BCMA/CD19 CAR-T cells
PhasePhase1
Recruitment statusUnknown
TitleBCMA-CD19 cCAR in Multiple Myeloma and Plasmacytoid Lymphoma
Year2019
CountryUnited States
Company sponsoriCell Gene Therapeutics
Other ID(s)ICG185-001
Vector information
Vectorlentivirus

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 2~10E6 cells/kg
Pts 12
Age Child, Adult, Older_Adult

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