Gene symbol | TNFRSF17 | Synonyms | BCM, BCMA, CD269, TNFRSF13A | Type of gene | protein-coding | |
Chromosome | 16 | Map location | 16p13.13 | dbXrefs | Entrez:608 MIM:109545 HGNC:HGNC:11913 Ensembl:ENSG00000048462 AllianceGenome:HGNC:11913 | |
Description | TNF receptor superfamily member 17 |
Gene symbol | PDCD1 | Synonyms | CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1 | Type of gene | protein-coding | |
Chromosome | 2 | Map location | 2q37.3 | dbXrefs | Entrez:5133 MIM:600244 HGNC:HGNC:8760 Ensembl:ENSG00000188389 AllianceGenome:HGNC:8760 | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | |||||
Description | programmed cell death 1 |
GTO ID | GTC2245 |
Trial ID | NCT04162119 |
Disease | Multiple Myeloma |
Altered gene | BCMA|PD1 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | BCMA/PD1 CAR-T cells |
Phase | Phase2 |
Recruitment status | Unknown |
Title | Safety and Efficiency Study of BCMA-PD1-cells in Relapsed/Refractory Multiple Myeloma |
Year | 2019 |
Country | China |
Company sponsor | Chinese PLA General Hospital |
Other ID(s) | HNYY-XYK-01 |
Cohort 1 | |||||||
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