Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
Gene symbol | MS4A1 | Synonyms | B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11q12.2 | dbXrefs | |
Description | membrane spanning 4-domains A1 |
GTO ID | GTC2244 |
Trial ID | NCT04160195 |
Disease | B-Cell Chronic Lymphocytic Leukemia | B-Cell Lymphoma | Non-Hodgkin's Lymphoma |
Altered gene | CD19|CD20 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CD19/CD20 CAR-T cells |
Generation | 2nd |
Phase | Phase1 |
Recruitment status | Terminated |
Title | T Cells Expressing Fully-human Anti-CD19 and Anti-CD20 Chimeric Antigen Receptors for Treating B-cell Malignancies and Hodgkin Lymphoma |
Year | 2020 |
Country | United States |
Company sponsor | National Cancer Institute (NCI) |
Other ID(s) | 200008|20-C-0008 |
Cohort 1 | |||||||||
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