Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol MS4A1 Synonyms B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 Type of gene protein-coding
Description membrane spanning 4-domains A1

GTO ID GTC2244
Trial ID NCT04160195
Disease B-Cell Chronic Lymphocytic Leukemia | B-Cell Lymphoma | Non-Hodgkin's Lymphoma
Altered gene CD19|CD20
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD20 CAR-T cells
Generation2nd
PhasePhase1
Recruitment statusTerminated
TitleT Cells Expressing Fully-human Anti-CD19 and Anti-CD20 Chimeric Antigen Receptors for Treating B-cell Malignancies and Hodgkin Lymphoma
Year2020
CountryUnited States
Company sponsorNational Cancer Institute (NCI)
Other ID(s)200008|20-C-0008

Clinical Result

Cohort 1
Administration route None
Dosage 0.66E6 cells/kg
Pts 2
Age Adult, Older_Adult

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