Gene symbol | IL3RA | Synonyms | CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra | Type of gene | protein-coding |
Chromosome | X|Y | Map location | X;Y | dbXrefs | |
Description | interleukin 3 receptor subunit alpha |
Gene symbol | CD33 | Synonyms | CD33rSiglec, SIGLEC-3, SIGLEC3, p67 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.41 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | CD33 molecule |
GTO ID | GTC2238 |
Trial ID | NCT04156256 |
Disease | Chronic Myeloid Leukemia | Acute Myeloid Leukemia | Myelodysplastic Syndrome | Myeloproliferative Neoplasm | Hematologic Cancer |
Altered gene | CD123|CD33 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CD123/CD33 CAR-T cells |
Phase | Early_Phase1 |
Recruitment status | Unknown |
Title | CD123-CD33 cCAR in Patients With Relapsed and/or Refractory, High Risk Hematologic Malignancies |
Year | 2018 |
Country | China |
Company sponsor | iCell Gene Therapeutics |
Other ID(s) | ICG136-001 |
Vector information | |||
|
Cohort 1 | |||||||
|