Basic Information

Gene symbol IL3RA Synonyms CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra Type of gene protein-coding
Description interleukin 3 receptor subunit alpha

Gene symbol CD33 Synonyms CD33rSiglec, SIGLEC-3, SIGLEC3, p67 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description CD33 molecule

GTO ID GTC2238
Trial ID NCT04156256
Disease Chronic Myeloid Leukemia | Acute Myeloid Leukemia | Myelodysplastic Syndrome | Myeloproliferative Neoplasm | Hematologic Cancer
Altered gene CD123|CD33
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD123/CD33 CAR-T cells
PhaseEarly_Phase1
Recruitment statusUnknown
TitleCD123-CD33 cCAR in Patients With Relapsed and/or Refractory, High Risk Hematologic Malignancies
Year2018
CountryChina
Company sponsoriCell Gene Therapeutics
Other ID(s)ICG136-001
Vector information
Vectorlentivirus

Clinical Result

Cohort 1
Administration route None
Pts 20
Age Child, Adult, Older_Adult

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