Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC2237
Trial ID NCT04156243
Disease B-Cell Lymphoma | B-Cell Leukemia
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19 CARvac T cells
PhaseEarly_Phase1
Recruitment statusUnknown
TitleCD19 CARvac T Cells for Patients With Relapsed / Refractory B Cell Malignancies
Year2018
CountryUnited States
Company sponsoriCell Gene Therapeutics
Other ID(s)ICG134-001
Vector information
Vectorlentivirus

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1E6 cells/kg
Pts 20
Age Child, Adult, Older_Adult
Lymph depletion Yes
References PMID: 32840736

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