Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol MS4A1 Synonyms B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 Type of gene protein-coding
Description membrane spanning 4-domains A1

GTO ID GTC2235
Trial ID NCT04156178
Disease B-Cell Lymphoma | B-Cell Leukemia
Altered gene CD19|CD20
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD20 CAR-T cells
PhaseEarly_Phase1
Recruitment statusUnknown
TitleCD20-CD19 Compound CAR (cCAR) T Cells for Patients With Relapsed /Refractory B Cell Malignancies
Year2018
CountryUnited States
Company sponsoriCell Gene Therapeutics
Other ID(s)ICG133-001
Vector information
Vectorlentivirus

Clinical Result

Cohort 1
Administration route intravenous infusion
Pts 12
Age Child, Adult, Older_Adult
Lymph depletion Yes

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