Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

GTO ID GTC2234
Trial ID NCT04155749
Disease Multiple Myeloma
Altered gene BCMA
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment BCMA CAR-T cells
PhasePhase1
Recruitment statusRecruiting
TitleMaster Protocol for the Phase 1 Study of Cell Therapies in Multiple Myeloma
Year2019
CountryUnited States
Company sponsorArcellx, Inc.
Other ID(s)ARC-101

Clinical Result

Cohort 1
Administration route None
Pts 9
Age Adult, Older_Adult
Outcome With a median follow-up of 7.43 months for survivors, 6/9 patients were alive with 4/9 showing ongoing responses
Adverse reactions 1/6(CRS); 5/9(ICANS)
References DOI: 10.1182/blood-2021-148444

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