Basic Information

Gene symbol EGFR Synonyms ERBB, ERBB1, ERRP, HER1, NISBD2, PIG61, mENA Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description epidermal growth factor receptor

GTO ID GTC2231
Trial ID NCT04153799
Disease Lung Non-Small Cell Carcinoma
Altered gene EGFR
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment EGFR CAR-T cells
PhasePhase1
Recruitment statusUnknown
TitleStudy of CXCR5 Modified EGFE Chimeric Antigen Receptor Autologous T Cells in EGFR- Positive Patients With Advanced Non-small Cell Lung Cancer
Year2019
CountryChina
Company sponsorSun Yat-sen University
Other ID(s)B2019-136-01

Clinical Result

Cohort 1
Administration route None
Dosage 0.5E6 cells/kg, 1.58E6 cells/kg, 5E6 cells/kg
Donor type Autologous
Pts 11
Age Adult, Older_Adult

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