Basic Information


GTO ID GTC2216
Trial ID NCT04135092
Disease Metastatic Cancer
Altered gene Neoantigen
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment Neoantigen TCR-T cells
PhasePhase2
Recruitment statusNo Longer Available
TitleSingle Patient Protocol: A Phase II Study Using the Administration of Autologous T-Cells Genetically Engineered to Express T-Cell Receptors Reactive Against Mutated Neoantigens in a Patient With Metastatic Cancer Plus the Administration of Pembrolizumab
Year2019
CountryUnited States
Company sponsorNational Institutes of Health Clinical Center (CC)
Other ID(s)209950

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Age Adult, Older_Adult
Lymph depletion Yes

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