Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC2214
Trial ID NCT04134117
Disease Central Nervous System Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment Kymriah|Tisagenlecleucel
Generation2nd
PhasePhase1
Recruitment statusUnknown
TitleTisagenlecleucel In Primary CNS Lymphoma
Year2019
CountryUnited States
Company sponsorMatthew J. Frigault, M.D.
Other ID(s)19-319
Vector information
Vectorlentivirus
ConstructscFv-4-1BB-CD3ζ

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Autologous
Pts 6
Age Adult, Older_Adult
Lymph depletion Yes

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