Basic Information

Gene symbol IL13RA2 Synonyms CD213A2, CT19, IL-13R, IL13BP Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description interleukin 13 receptor subunit alpha 2

GTO ID GTC2201
Trial ID NCT04119024
Disease Susceptibility to Cutaneous Malignant Melanoma 3
Altered gene IL13RA2
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment IL13Ra2 CAR-T cells
Generation2nd
PhasePhase1
Recruitment statusRecruiting
TitleGene Modified Immune Cells (IL13Ralpha2 CAR T Cells) After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma
Year2019
CountryUnited States
Company sponsorJonsson Comprehensive Cancer Center
Other ID(s)19-001145|NCI-2019-05764|19-001145
Vector information
Vectorlentivirus
ConstructscFv-4-1BB-CD3ζ

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Autologous
Pts 24
Age Adult, Older_Adult
Lymph depletion Yes

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