Basic Information

Gene symbol KLRK1 Synonyms CD314, D12S2489E, KLR, NKG2-D, NKG2D Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description killer cell lectin like receptor K1

GTO ID GTC2198
Trial ID NCT04107142
Disease Sarcoma | Triple-Receptor Negative Breast Cancer | Colorectal Cancer | Nasopharyngeal Disease | Prostate Cancer | Stomach Cancer
Altered gene NKG2D
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CTM-N2D
PhasePhase1
Recruitment statusUnknown
TitleHaplo / Allogeneic NKG2DL-targeting Chimeric Antigen Receptor-grafted γδ T Cells for Relapsed or Refractory Solid Tumour
Year2019
CountrySingapore
Company sponsorCytoMed Therapeutics Pte Ltd
Other ID(s)CTM-N2D

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 3E8~3E9 cells
Donor type Allogeneic
Pts 10
Age Adult, Older_Adult

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