Basic Information


GTO ID GTC2195
Trial ID NCT04102436
Disease Lung Non-Small Cell Carcinoma | Ovarian Cancer | Genitourinary Cancer | Breast Cancer
Altered gene Neoantigen
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment Neoantigen TCR-T cells
PhasePhase2
Recruitment statusRecruiting
TitleA Phase II Study Using the Administration of Autologous T-Cells Engineered Using the Sleeping Beauty Transposon/Transposase System to Express T-Cell Receptors Reactive Against Mutated Neoantigens in Patients With Metastatic Cancer
Year2019
CountryUnited States
Company sponsorNational Cancer Institute (NCI)
Other ID(s)190143|19-C-0143
Vector information
VectorSleeping Beauty system

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Age Adult, Older_Adult
Lymph depletion Yes

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