Basic Information



GTO ID GTC2193
Trial ID NCT04099797
Disease Embryonal Cancer | High Grade Glioma | Ependymal Tumor
Altered gene C7R|GD2
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment GD2.C7R T cells
PhasePhase1
Recruitment statusRecruiting
TitleC7R-GD2.CAR T Cells for Patients With GD2-expressing Brain Tumors (GAIL-B)
Year2020
CountryUnited States
Company sponsorBaylor College of Medicine
Other ID(s)H-45668 GAIL-B
Vector information
Vectorretrovirus

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 5E6 cells/dose, 1E7 cells/dose, 2E7 cells/dose, 5E7 cells/dose
Donor type Autologous
Pts 34
Age Child, Adult
Lymph depletion Yes

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