Basic Information

Gene symbol CD44 Synonyms CDW44, CSPG8, ECM-III, ECMR-III, H-CAM, HCELL, HUTCH-1, HUTCH-I, Hermes-1, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD44 molecule (IN blood group)

GTO ID GTC2192
Trial ID NCT04097301
Disease Acute Myeloid Leukemia | Multiple Myeloma
Altered gene CD44
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment MLM-CAR44.1 T-cells
PhasePhase1|Phase2
Recruitment statusTerminated
TitleStudy of CAR T-cell Therapy in Acute Myeloid Leukemia and Multiple Myeloma
Year2019
CountryItaly
Company sponsorAGC Biologics S.p.A.
Other ID(s)EURE-CART-1|2018-000813-19

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 0.5E6 cells/kg, 1E6 cells/kg, 2E6 cells/kg
Pts 8
Age Child, Adult, Older_Adult
Lymph depletion Yes

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