Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC2191
Trial ID NCT04094766
Disease B-Cell Acute Lymphoblastic Leukemia
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD22 CAR-T cells
PhasePhase1
Recruitment statusWithdrawn
TitleSafety and Efficacy of Dual Specificity CD19 and CD22 CAR-T Cell Immunotherapy in R/R Acute B Lymphoblastic Leukemia
Year2017
CountryChina
Company sponsorSecond Affiliated Hospital of Xi'an Jiaotong University
Other ID(s)XJTU-BLLCAR-L10D

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 0.5E6 cells/kg, 1.5E6 cells/kg, 2E6 cells/kg
Pts 0
Age Child, Adult

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