| Gene symbol | GPC3 | Synonyms | DGSX, GTR2-2, MXR7, OCI-5, SDYS, SGB, SGBS, SGBS1 | Type of gene | protein-coding | |
| Chromosome | X | Map location | Xq26.2 | dbXrefs | Entrez:2719 MIM:300037 HGNC:HGNC:4451 Ensembl:ENSG00000147257 AllianceGenome:HGNC:4451 | |
| Description | glypican 3 | |||||
| GTO ID | GTC2189 |
| Trial ID | NCT04093648 |
| Disease | Hepatoblastoma | Hepatocellular Carcinoma |
| Altered gene | GPC3 |
| Therapeutic/Target gene | Target gene |
| Therapy | CAR-T cell |
| Treatment | TEGAR T cells |
| Generation | 2nd |
| Phase | Phase1 |
| Recruitment status | Withdrawn |
| Title | T Cells co- Expressing a Second Generation Glypican 3-specific Chimeric Antigen Receptor With Cytokines Interleukin-21 and 15 as Immunotherapy for Patients With Liver Cancer (TEGAR) |
| Year | 2020 |
| Country | United States |
| Company sponsor | Baylor College of Medicine |
| Other ID(s) | H-43874 TEGAR |
| Vector information | |||
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| Cohort 1 | |||||||||||
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