Basic Information


GTO ID GTC2184
Trial ID NCT04089215
Disease Diffuse Large B-Cell Lymphoma | Follicular Lymphoma | Non-Hodgkin's Lymphoma
Altered gene GD2
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment 1RG CAR-T cells
Generation2nd
PhasePhase1
Recruitment statusCompleted
TitleA Phase I Trial of Anti-GD2 T-cells (1RG-CART)
Year2019
CountryUnited Kingdom
Company sponsorShanghai Ming Ju Biotechnology Co., Ltd.
Other ID(s)JWCAR029-002
Vector information
Vectorlentivirus
ConstructscFv-4-1BB-CD3ζ

Clinical Result

Cohort 1
Administration route None
Dosage 1E8 cells, 1.5E8 cells
Donor type Autologous
Pts 82
Age Adult, Older_Adult

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