Basic Information

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC2182
Trial ID NCT04088864
Disease Lymphoma | Childhood B-Cell Acute Lymphoblastic Leukemia | B-Cell Lymphoma
Altered gene CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD22 CAR-T cells
PhasePhase1
Recruitment statusSuspended
TitleCD22-CAR T Cells in Children and Young Adults With B Cell Malignancies
Year2020
CountryUnited States
Company sponsorStanford University
Other ID(s)IRB-50878|CCT6003|IRB-50878|NCI-2019-07285
Vector information
Vectorlentivirus

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1E6 cells/kg
Donor type Autologous
Pts 52
Age Child, Adult
Lymph depletion Yes

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