Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC2176
Trial ID NCT04071366
Disease Follicular Lymphoma | Relapsed/Refractory Diffuse Large B-Cell Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment YesCAR-Ta|Axicabtagene Ciloleucel|axi-cel
Generation2nd
PhasePhase2
Recruitment statusRecruiting
TitleA Study of Itacitinib for the Prevention of Cytokine Release Syndrome Induced by Immune Effector Cell Therapy
Year2019
CountryUnited States
Company sponsorIncyte Corporation
Other ID(s)INCB 39110-211
Vector information
Vectorlentivirus
ConstructscFv-CD28-CD3ζ

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Autologous
Pts 108
Age Child, Adult, Older_Adult
Lymph depletion Yes

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