Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC2168
Trial ID NCT04049513
Disease B-Cell Non-Hodgkin's Lymphoma | Follicular Lymphoma | Mantle Cell Lymphoma | Primary Mediastinal B-Cell Lymphoma | Diffuse Large B-Cell Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment WZTL-002
Generation3rd
PhasePhase1
Recruitment statusRecruiting
TitleENABLE (Engaging Toll-like Receptor Signalling for B-cell Lymphoma Chimeric Antigen Receptor Therapy)
Year2019
CountryNew Zealand
Company sponsorMalaghan Institute of Medical Research
Other ID(s)WZTL002-1|U1111-1216-2053

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 5E4 cells/kg
Donor type Autologous
Pts 30
Age Child, Adult, Older_Adult
Lymph depletion Yes

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