Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol MS4A1 Synonyms B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 Type of gene protein-coding
Description membrane spanning 4-domains A1

GTO ID GTC2167
Trial ID NCT04049383
Disease Childhood B-Cell Acute Lymphoblastic Leukemia | B-Cell Acute Lymphoblastic Leukemia | Acute Lymphoblastic Leukemia
Altered gene CD19|CD20
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD20 CAR-T cells
Generation2nd
PhasePhase1
Recruitment statusRecruiting
TitleCAR-20/19-T Cells in Pediatric and Young Adult Patients With Relapsed/Refractory B Cell ALL
Year2020
CountryUnited States
Company sponsorMedical College of Wisconsin
Other ID(s)CAR-20/19-T

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 5E5 cells/kg, 1E6 cells/kg, 2.5E6 cells/kg,
Donor type Autologous
Pts 24
Age Child, Adult

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