Basic Information

Gene symbol MAGEA4 Synonyms CT1.4, MAGE-41, MAGE-X2, MAGE4, MAGE4A, MAGE4B Type of gene protein-coding
Description MAGE family member A4

GTO ID GTC2160
Trial ID NCT04044768
Disease Synovial Sarcoma | Myxoid Liposarcoma
Altered gene MAGE-A4
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment MAGE-A4 TCR-T cells
HLAHLA-A*02
PhasePhase2
Recruitment statusRecruiting
TitleA Phase 2 Single Arm Open-Label Clinical Trial of ADP-A2M4 SPEAR T Cells in Subjects With Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma
Year2019
CountryUnited States
Company sponsorAdaptimmune
Other ID(s)ADP 0044-002

Clinical Result

Cohort 1
Administration route infusion
Dosage 0.1~1E8 cells
Donor type autologous
Age Child, Adult, Older_Adult
Lymph depletion Yes

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