Basic Information

Gene symbol MS4A1 Synonyms B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 Type of gene protein-coding
Description membrane spanning 4-domains A1

GTO ID GTC2150
Trial ID NCT04030195
Disease Chronic Lymphocytic Leukemia | Non-Hodgkin's Lymphoma | Small Lymphocytic Lymphoma | Human Monocytic Ehrlichiosis
Altered gene CD20
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment PBCAR20A
PhasePhase1|Phase2
Recruitment statusCompleted
TitleDose-escalation Study of Safety of PBCAR20A in Subjects With r/r NHL or r/r CLL/SLL
Year2020
CountryUnited States
Company sponsorPrecision BioSciences, Inc.
Other ID(s)PBCAR20A-01

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1E6 cells/kg, 240E6 cells, 480E6 cells
Donor type Allogeneic
Pts 18
Age Adult, Older_Adult
Lymph depletion Yes

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