Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
Gene symbol | CD22 | Synonyms | SIGLEC-2, SIGLEC2 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.12 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | CD22 molecule |
GTO ID | GTC2149 |
Trial ID | NCT04029038 |
Disease | Non-Hodgkin's Lymphoma | Chronic Lymphocytic Leukemia | B-Cell Acute Lymphoblastic Leukemia |
Altered gene | CD19|CD22 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CD19/CD22 CAR-T cells |
Phase | Phase1|Phase2 |
Recruitment status | Not Recruiting |
Title | Modified Immune Cells (CD19-CD22 CAR T Cells) in Treating Patients With Recurrent or Refractory CD19 Positive, CD22 Positive Leukemia or Lymphoma |
Year | 2020 |
Country | United States |
Company sponsor | M.D. Anderson Cancer Center |
Other ID(s) | 2019-0042|NCI-2019-04229|2019-0042|P30CA016672 |
Cohort 1 | |||||||||||
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