Basic Information

Gene symbol MUC1 Synonyms ADMCKD, ADMCKD1, ADTKD2, CA 15-3, CD227, Ca15-3, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description mucin 1, cell surface associated

GTO ID GTC2147
Trial ID NCT04025216
Disease Lung Non-Small Cell Carcinoma | Pancreatic Ductal Adenocarcinoma | Multiple Myeloma | Ovarian Cancer | Fallopian Tube Cancer | Triple-Receptor Negative Breast Cancer
Altered gene MUC1
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment TnMUC1 CAR-T cells
PhasePhase1
Recruitment statusTerminated
TitleA Study of CART-TnMUC1 in Patients With TnMUC1-Positive Advanced Cancers
Year2019
CountryUnited States
Company sponsorTmunity Therapeutics
Other ID(s)CART-TnMUC1-01

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Autologous
Pts 6
Age Adult, Older_Adult
Lymph depletion Yes
Outcome 3/6(SD)
References DOI: 10.1200/JCO.2021.39.15_suppl.e14513

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