Gene symbol | MUC1 | Synonyms | ADMCKD, ADMCKD1, ADTKD2, CA 15-3, CD227, Ca15-3, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM | Type of gene | protein-coding |
Chromosome | 1 | Map location | 1q22 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | mucin 1, cell surface associated |
GTO ID | GTC2147 |
Trial ID | NCT04025216 |
Disease | Lung Non-Small Cell Carcinoma | Pancreatic Ductal Adenocarcinoma | Multiple Myeloma | Ovarian Cancer | Fallopian Tube Cancer | Triple-Receptor Negative Breast Cancer |
Altered gene | MUC1 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | TnMUC1 CAR-T cells |
Phase | Phase1 |
Recruitment status | Terminated |
Title | A Study of CART-TnMUC1 in Patients With TnMUC1-Positive Advanced Cancers |
Year | 2019 |
Country | United States |
Company sponsor | Tmunity Therapeutics |
Other ID(s) | CART-TnMUC1-01 |
Cohort 1 | |||||||||||||||
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