Gene symbol | MUC1 | Synonyms | ADMCKD, ADMCKD1, ADTKD2, CA 15-3, CD227, Ca15-3, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM | Type of gene | protein-coding |
Chromosome | 1 | Map location | 1q22 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | mucin 1, cell surface associated |
GTO ID | GTC2146 |
Trial ID | NCT04020575 |
Disease | Sporadic Breast Cancer |
Altered gene | MUC1 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | huMNC2-CAR44|huMNC2-CAR22 |
Generation | 2nd |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | Autologous huMNC2-CAR44 or huMNC2-CAR22 T Cells for Breast Cancer Targeting Cleaved Form of MUC1 (MUC1*) |
Year | 2020 |
Country | United States |
Company sponsor | Minerva Biotechnologies Corporation |
Other ID(s) | 10038 |
Vector information | |||||
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Cohort 1 | |||||||||
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